mardi 15 décembre 2015

Crohn's Disease and Gallstones (Black vs Cholesterol)

also, uptodate says the following: Crohn disease — The prevalence of gallstones is increased in patients with Crohn disease [75-78]. In a population based study in Sweden, for example, gallstones were detected in 26 percent of patients with Crohn disease, which was approximately twice as frequent as the general population [75]. Gallstones in patients with ileal Crohn disease (or those who have undergone ileal resection) are frequently pigment based, reflecting an increased concentration of bilirubin conjugates, unconjugated bilirubin, and total calcium in the gallbladder bile due perhaps to altered enterohepatic cycling of bilirubin [76

So I guess its billirubin cycling, however, what about ileal resection disrupting the BILE ACID enterohepatic cycling??

This baffles me

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Crohn's Disease and Gallstones (Black vs Cholesterol)

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