If V/Q is less than 1, then A-a gradient will increase.
e.g. pulmonary edema: fluid in alveoli prevents capillary blood from being 100% saturated, then that blood mixes with saturated blood from non-fluid filled alveoli, lowering PaO2.
But if I breathe really slowly, doesn't this also decrease PaO2?
Blood is being perfused at a normal rate, but ventilation has decreased, right? And since PAO2 is...
Why does hypoventilation not increase A-a gradient?
Why does hypoventilation not increase A-a gradient?
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